Interactions médicamenteuses
Disopyramide + Octreotide
Gravité: Majeure
Disopyramide and Octreotide: major interaction.
Dernière mise à jour
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Résumé
Octreotide can cause bradycardia and conduction abnormalities and has been associated with QT prolongation, while disopyramide prolongs QT and can cause torsades de pointes. Combined use may raise arrhythmia risk, especially with electrolyte disturbances.
Ce que signifie cette interaction, en termes simples
Disopyramide and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Disopyramide belongs to Cardiovascular; Octreotide belongs to Endocrine.
Pourquoi elle survient
Additive effects on cardiac repolarization and conduction, plus octreotide-related bradycardia.
Conduite à tenir
Avoid if possible; otherwise obtain baseline and follow-up ECGs and correct potassium and magnesium.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Octreotide
- Adagrasib + Octreotide Majeure
- Amisulpride + Octreotide Majeure
- Arsenic trioxide + Octreotide Majeure
- Artemether / lumefantrine + Octreotide Majeure
- Artemether + Octreotide Majeure
- Ceritinib + Octreotide Majeure
Autres interactions de Disopyramide
- Amisulpride + Disopyramide Contre-indiquée
- Desipramine + Disopyramide Contre-indiquée
- Disopyramide + Dronedarone Contre-indiquée
- Disopyramide + Itraconazole Contre-indiquée
- Disopyramide + Ketoconazole Contre-indiquée
- Disopyramide + Maprotiline Contre-indiquée
Questions fréquentes
Can I take Disopyramide with Octreotide?
MediHelp rates the interaction as major. Disopyramide and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Octreotide can cause bradycardia and conduction abnormalities and has been associated with QT prolongation, while disopyramide prolongs QT and can cause torsades de pointes. Combined use may raise arrhythmia risk, especially with electrolyte disturbances.
How serious is the interaction between Disopyramide and Octreotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise obtain baseline and follow-up ECGs and correct potassium and magnesium.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
