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Interactions médicamenteuses

Baloxavir marboxil + Magnesium hydroxide

Gravité: Modérée

Baloxavir marboxil and Magnesium hydroxide: moderate interaction.

Dernière mise à jour

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Résumé

Baloxavir can chelate polyvalent cations such as magnesium in the gut, which may reduce its absorption and antiviral exposure. This could lessen treatment effectiveness for influenza.

Ce que signifie cette interaction, en termes simples

Baloxavir marboxil and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Baloxavir marboxil belongs to Anti Virals; Magnesium hydroxide belongs to Gastrointestinal Tract.

Niveau de preuve: Moderate

Pourquoi elle survient

Chelation of baloxavir by polyvalent cations in the gastrointestinal tract reduces absorption.

Conduite à tenir

Avoid taking baloxavir with magnesium-containing antacids or laxatives. If needed, give baloxavir at least 2 hours apart from the antacid.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Baloxavir marboxil with Magnesium hydroxide?

MediHelp rates the interaction as moderate. Baloxavir marboxil and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir can chelate polyvalent cations such as magnesium in the gut, which may reduce its absorption and antiviral exposure. This could lessen treatment effectiveness for influenza.

How serious is the interaction between Baloxavir marboxil and Magnesium hydroxide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir with magnesium-containing antacids or laxatives. If needed, give baloxavir at least 2 hours apart from the antacid.

What other medicines interact with Magnesium hydroxide?

MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.

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