Interactions médicamenteuses
Bcg vaccine live + Everolimus
Gravité: Contre-indiquée
Bcg vaccine live and Everolimus: contraindicated interaction.
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Résumé
Live BCG vaccine in a patient on everolimus risks disseminated BCG infection because of impaired cell-mediated immunity. The vaccine response may also be reduced.
Ce que signifie cette interaction, en termes simples
Bcg vaccine live and Everolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
mTOR inhibition-related immunosuppression allows uncontrolled replication of the live attenuated mycobacteria.
Conduite à tenir
Do not give live BCG vaccine during everolimus therapy. Complete any needed live vaccinations before starting treatment, observing the recommended interval.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Everolimus
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Everolimus + Levoketoconazole Contre-indiquée
- Everolimus + Measles mumps and rubella vaccine live Contre-indiquée
- Everolimus + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Everolimus + Measles vaccine Contre-indiquée
- Everolimus + Ritonavir Contre-indiquée
Questions fréquentes
Can I take Bcg vaccine live with Everolimus?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Everolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live BCG vaccine in a patient on everolimus risks disseminated BCG infection because of impaired cell-mediated immunity. The vaccine response may also be reduced.
How serious is the interaction between Bcg vaccine live and Everolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live BCG vaccine during everolimus therapy. Complete any needed live vaccinations before starting treatment, observing the recommended interval.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole, Measles mumps and rubella vaccine live. The full list is on the Everolimus page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
