Interactions médicamenteuses
Bcg vaccine live + Prednisone
Gravité: Contre-indiquée
Bcg vaccine live and Prednisone: contraindicated interaction.
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Résumé
BCG is a live attenuated vaccine, and immunosuppressive doses of prednisone may allow disseminated BCG infection and reduce the immune response. Vaccination is generally avoided during high-dose corticosteroid therapy.
Ce que signifie cette interaction, en termes simples
Bcg vaccine live and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid immunosuppression impairs control of live attenuated organism replication and reduces vaccine response.
Conduite à tenir
Avoid live BCG during immunosuppressive prednisone therapy and delay vaccination until the drug has been stopped for the interval stated in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Prednisone
- Measles vaccine + Prednisone Contre-indiquée
- Mifepristone + Prednisone Contre-indiquée
- Prednisone + Radium-223 dichloride Contre-indiquée
- Prednisone + Smallpox vaccine live Contre-indiquée
- Adenovirus types 4 and 7 live + Prednisone Majeure
- Aldesleukin + Prednisone Majeure
Questions fréquentes
Can I take Bcg vaccine live with Prednisone?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated vaccine, and immunosuppressive doses of prednisone may allow disseminated BCG infection and reduce the immune response. Vaccination is generally avoided during high-dose corticosteroid therapy.
How serious is the interaction between Bcg vaccine live and Prednisone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG during immunosuppressive prednisone therapy and delay vaccination until the drug has been stopped for the interval stated in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Measles vaccine, Mifepristone, Radium-223 dichloride. The full list is on the Prednisone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
