Interactions médicamenteuses
Prednisone + Radium-223 dichloride
Gravité: Contre-indiquée
Prednisone and Radium-223 dichloride: contraindicated interaction.
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Résumé
Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.
Ce que signifie cette interaction, en termes simples
Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Prednisone belongs to Endocrine; Radium-223 dichloride belongs to Miscellaneous.
Pourquoi elle survient
The mechanism is not established; additive bone toxicity has been proposed.
Conduite à tenir
Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Radium-223 dichloride
- Abiraterone + Radium-223 dichloride Contre-indiquée
- Prednisolone + Radium-223 dichloride Contre-indiquée
- Radium-223 dichloride + Siponimod Modérée
- Calcium + Radium-223 dichloride Mineure
- Radium-223 dichloride + Vitamin d Mineure
Autres interactions de Prednisone
- Bcg vaccine live + Prednisone Contre-indiquée
- Measles vaccine + Prednisone Contre-indiquée
- Mifepristone + Prednisone Contre-indiquée
- Prednisone + Smallpox vaccine live Contre-indiquée
- Adenovirus types 4 and 7 live + Prednisone Majeure
- Aldesleukin + Prednisone Majeure
Questions fréquentes
Can I take Prednisone with Radium-223 dichloride?
MediHelp rates the interaction as contraindicated. Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.
How serious is the interaction between Prednisone and Radium-223 dichloride?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.
What other medicines interact with Radium-223 dichloride?
MediHelp also lists interactions of Radium-223 dichloride with, for example, Abiraterone, Prednisolone, Siponimod. The full list is on the Radium-223 dichloride page.
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