Interactions médicamenteuses
Measles vaccine + Prednisone
Gravité: Contre-indiquée
Measles vaccine and Prednisone: contraindicated interaction.
Dernière mise à jour Sources: US FDA label
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Résumé
Measles vaccine is live attenuated, and immunosuppressive doses of prednisone may allow uncontrolled vaccine virus replication and also reduce the immune response. Live vaccination is generally avoided during high-dose steroid therapy.
Ce que signifie cette interaction, en termes simples
Measles vaccine and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and reduces vaccine response.
Conduite à tenir
Avoid the live measles vaccine during immunosuppressive prednisone therapy and defer it until the steroid has been stopped for the interval in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Références
Autres interactions de Prednisone
- Bcg vaccine live + Prednisone Contre-indiquée
- Mifepristone + Prednisone Contre-indiquée
- Prednisone + Radium-223 dichloride Contre-indiquée
- Prednisone + Smallpox vaccine live Contre-indiquée
- Adenovirus types 4 and 7 live + Prednisone Majeure
- Aldesleukin + Prednisone Majeure
Questions fréquentes
Can I take Measles vaccine with Prednisone?
MediHelp rates the interaction as contraindicated. Measles vaccine and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and immunosuppressive doses of prednisone may allow uncontrolled vaccine virus replication and also reduce the immune response. Live vaccination is generally avoided during high-dose steroid therapy.
How serious is the interaction between Measles vaccine and Prednisone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live measles vaccine during immunosuppressive prednisone therapy and defer it until the steroid has been stopped for the interval in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Mifepristone, Radium-223 dichloride. The full list is on the Prednisone page.
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