Interactions médicamenteuses
Belladonna and opium + Chlordiazepoxide-clidinium
Gravité: Majeure
Belladonna and opium and Chlordiazepoxide-clidinium: major interaction.
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Résumé
Opium contains opioids that combined with a benzodiazepine increase risk of profound sedation, respiratory depression and death. Belladonna also adds anticholinergic effects to clidinium.
Ce que signifie cette interaction, en termes simples
Belladonna and opium and Chlordiazepoxide-clidinium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive CNS and respiratory depression plus additive anticholinergic effects.
Conduite à tenir
Avoid combining where possible; otherwise use minimum doses and monitor respiratory status and sedation closely.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Chlordiazepoxide-clidinium
- Alfentanil + Chlordiazepoxide-clidinium Majeure
- Alprazolam + Chlordiazepoxide-clidinium Majeure
- Amobarbital + Chlordiazepoxide-clidinium Majeure
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium Majeure
- Brexanolone + Chlordiazepoxide-clidinium Majeure
- Buprenorphine buccal + Chlordiazepoxide-clidinium Majeure
Questions fréquentes
Can I take Belladonna and opium with Chlordiazepoxide-clidinium?
MediHelp rates the interaction as major. Belladonna and opium and Chlordiazepoxide-clidinium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opium contains opioids that combined with a benzodiazepine increase risk of profound sedation, respiratory depression and death. Belladonna also adds anticholinergic effects to clidinium.
How serious is the interaction between Belladonna and opium and Chlordiazepoxide-clidinium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; otherwise use minimum doses and monitor respiratory status and sedation closely.
What other medicines interact with Chlordiazepoxide-clidinium?
MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
