Interactions médicamenteuses
Betaxolol + Bismuth subsalicylate
Gravité: Modérée
Betaxolol and Bismuth subsalicylate: moderate interaction.
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Résumé
Salicylate from bismuth subsalicylate may blunt the antihypertensive effect of betaxolol by reducing renal prostaglandin synthesis and promoting fluid retention. The effect is mostly relevant with repeated or high doses.
Ce que signifie cette interaction, en termes simples
Betaxolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
Pourquoi elle survient
Salicylate inhibits prostaglandin synthesis, causing sodium and fluid retention that opposes the antihypertensive effect.
Conduite à tenir
Keep bismuth subsalicylate use short and monitor blood pressure if used repeatedly. Consider alternative therapy for prolonged use.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Bismuth subsalicylate
- Bismuth subsalicylate + Dichlorphenamide Majeure
- Bismuth subsalicylate + Warfarin Majeure
- Acetylsalicylic acid + Bismuth subsalicylate Modérée
- Amlodipine-benazepril + Bismuth subsalicylate Modérée
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Modérée
- Aspirin rectal + Bismuth subsalicylate Modérée
Autres interactions de Betaxolol
- Acebutolol + Betaxolol Majeure
- Aldesleukin + Betaxolol Majeure
- Amifostine + Betaxolol Majeure
- Amiodarone + Betaxolol Majeure
- Atenolol-chlorthalidone + Betaxolol Majeure
- Atenolol + Betaxolol Majeure
Questions fréquentes
Can I take Betaxolol with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Betaxolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Salicylate from bismuth subsalicylate may blunt the antihypertensive effect of betaxolol by reducing renal prostaglandin synthesis and promoting fluid retention. The effect is mostly relevant with repeated or high doses.
How serious is the interaction between Betaxolol and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep bismuth subsalicylate use short and monitor blood pressure if used repeatedly. Consider alternative therapy for prolonged use.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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