Interactions médicamenteuses
Bupropion + Selegiline transdermal
Gravité: Contre-indiquée
Bupropion and Selegiline transdermal: contraindicated interaction.
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Résumé
Combining bupropion with a monoamine oxidase inhibitor can cause hypertensive reactions due to increased catecholamine levels. The label contraindicates this combination.
Ce que signifie cette interaction, en termes simples
Bupropion and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Bupropion inhibits dopamine and norepinephrine reuptake while MAO inhibition reduces their breakdown, producing additive catecholaminergic effects.
Conduite à tenir
Do not coadminister. Allow at least 14 days between stopping the MAOI and starting bupropion, and likewise when switching in the other direction.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Bupropion
- Bupropion + Isocarboxazid Contre-indiquée
- Bupropion + Linezolid Contre-indiquée
- Bupropion + Phenelzine Contre-indiquée
- Bupropion + Rasagiline Contre-indiquée
- Bupropion + Selegiline Contre-indiquée
- Bupropion + Thioridazine Contre-indiquée
Questions fréquentes
Can I take Bupropion with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Bupropion and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combining bupropion with a monoamine oxidase inhibitor can cause hypertensive reactions due to increased catecholamine levels. The label contraindicates this combination.
How serious is the interaction between Bupropion and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister. Allow at least 14 days between stopping the MAOI and starting bupropion, and likewise when switching in the other direction.
What other medicines interact with Bupropion?
MediHelp also lists interactions of Bupropion with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Bupropion page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
