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Interactions médicamenteuses

Caffeine + Regadenoson

Gravité: Modérée

Caffeine and Regadenoson: moderate interaction.

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Résumé

Caffeine and other methylxanthines block adenosine receptors, which is how regadenoson produces coronary vasodilation. Recent caffeine intake can blunt the vasodilator response and lead to a false-negative or less reliable myocardial perfusion stress test.

Ce que signifie cette interaction, en termes simples

Caffeine and Regadenoson can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Caffeine belongs to Miscellaneous; Regadenoson belongs to Cardiovascular.

Niveau de preuve: High

Pourquoi elle survient

Competitive antagonism of adenosine A2A receptors by caffeine opposing the agonist action of regadenoson.

Conduite à tenir

Withhold caffeine and other methylxanthines (coffee, tea, cola, theophylline) for at least 12 hours before the stress test, or per local protocol. Reschedule the test if recent intake is confirmed.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Caffeine with Regadenoson?

MediHelp rates the interaction as moderate. Caffeine and Regadenoson can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Caffeine and other methylxanthines block adenosine receptors, which is how regadenoson produces coronary vasodilation. Recent caffeine intake can blunt the vasodilator response and lead to a false-negative or less reliable myocardial perfusion stress test.

How serious is the interaction between Caffeine and Regadenoson?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold caffeine and other methylxanthines (coffee, tea, cola, theophylline) for at least 12 hours before the stress test, or per local protocol. Reschedule the test if recent intake is confirmed.

What other medicines interact with Caffeine?

MediHelp also lists interactions of Caffeine with, for example, Ephedrine, Fezolinetant, Methylenedioxymethamphetamine. The full list is on the Caffeine page.

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