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Interactions médicamenteuses

Calcium gluconate + Digoxin

Gravité: Majeure

Calcium gluconate and Digoxin: major interaction.

Dernière mise à jour

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Résumé

Intravenous calcium gluconate in a digitalized patient may precipitate arrhythmias through additive effects on myocardial calcium handling, though it is less concentrated than calcium chloride.

Ce que signifie cette interaction, en termes simples

Calcium gluconate and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Calcium gluconate belongs to Gastrointestinal Tract; Digoxin belongs to Cardiovascular.

Niveau de preuve: Moderate

Pourquoi elle survient

Acute hypercalcemia augments digoxin-induced intracellular calcium loading and ventricular automaticity.

Conduite à tenir

Avoid IV calcium in patients on digoxin unless necessary; if given, infuse slowly with continuous ECG monitoring.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Calcium gluconate with Digoxin?

MediHelp rates the interaction as major. Calcium gluconate and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Intravenous calcium gluconate in a digitalized patient may precipitate arrhythmias through additive effects on myocardial calcium handling, though it is less concentrated than calcium chloride.

How serious is the interaction between Calcium gluconate and Digoxin?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid IV calcium in patients on digoxin unless necessary; if given, infuse slowly with continuous ECG monitoring.

What other medicines interact with Digoxin?

MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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