Interactions médicamenteuses
Digoxin + Lily of the valley
Gravité: Contre-indiquée
Digoxin and Lily of the valley: contraindicated interaction.
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Résumé
Lily of the valley (Convallaria majalis) contains cardiac glycosides such as convallatoxin. Combined with digoxin it causes additive glycoside effects and risk of digitalis toxicity with serious arrhythmias.
Ce que signifie cette interaction, en termes simples
Digoxin and Lily of the valley are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Additive Na+/K+-ATPase inhibition from plant cardiac glycosides and digoxin.
Conduite à tenir
Avoid lily of the valley preparations during digoxin therapy. If ingestion occurs, obtain ECG, potassium and digoxin level and manage as glycoside toxicity.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Digoxin
- Digoxin + Squill Contre-indiquée
- Adagrasib + Digoxin Majeure
- Amiodarone + Digoxin Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Majeure
- Amphotericin b deoxycholate + Digoxin Majeure
- Amphotericin b + Digoxin Majeure
Questions fréquentes
Can I take Digoxin with Lily of the valley?
MediHelp rates the interaction as contraindicated. Digoxin and Lily of the valley are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lily of the valley (Convallaria majalis) contains cardiac glycosides such as convallatoxin. Combined with digoxin it causes additive glycoside effects and risk of digitalis toxicity with serious arrhythmias.
How serious is the interaction between Digoxin and Lily of the valley?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid lily of the valley preparations during digoxin therapy. If ingestion occurs, obtain ECG, potassium and digoxin level and manage as glycoside toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Squill, Adagrasib, Amiodarone. The full list is on the Digoxin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
