Interactions médicamenteuses
Digoxin + Squill
Gravité: Contre-indiquée
Digoxin and Squill: contraindicated interaction.
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Résumé
Squill contains cardiac glycosides (scilliroside-type bufadienolides) with digoxin-like activity. Combined use produces additive effects and a high risk of digitalis toxicity, including arrhythmias, nausea and visual disturbances.
Ce que signifie cette interaction, en termes simples
Digoxin and Squill are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Additive inhibition of Na+/K+-ATPase from the glycosides in squill and digoxin.
Conduite à tenir
Avoid squill in patients taking digoxin. If exposure has occurred, check digoxin level, potassium and ECG.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Digoxin
- Digoxin + Lily of the valley Contre-indiquée
- Adagrasib + Digoxin Majeure
- Amiodarone + Digoxin Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Majeure
- Amphotericin b deoxycholate + Digoxin Majeure
- Amphotericin b + Digoxin Majeure
Questions fréquentes
Can I take Digoxin with Squill?
MediHelp rates the interaction as contraindicated. Digoxin and Squill are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Squill contains cardiac glycosides (scilliroside-type bufadienolides) with digoxin-like activity. Combined use produces additive effects and a high risk of digitalis toxicity, including arrhythmias, nausea and visual disturbances.
How serious is the interaction between Digoxin and Squill?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid squill in patients taking digoxin. If exposure has occurred, check digoxin level, potassium and ECG.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Adagrasib, Amiodarone. The full list is on the Digoxin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
