Aller au contenu
MediHelp
MediHelp Référence médicamenteuse

Interactions médicamenteuses

Carboplatin + Zidovudine

Gravité: Majeure

Carboplatin and Zidovudine: major interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Both agents suppress the bone marrow, and combined use increases the risk of anemia, neutropenia and thrombocytopenia. Carboplatin is particularly myelosuppressive.

Ce que signifie cette interaction, en termes simples

Carboplatin and Zidovudine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Carboplatin belongs to Oncology; Zidovudine belongs to Anti Virals.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive bone marrow suppression.

Conduite à tenir

Monitor full blood counts frequently, and consider an alternative to zidovudine in patients on myelosuppressive chemotherapy. Reduce doses or provide growth factor support as needed.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Carboplatin et Zidovudine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
Créer un compte gratuit Se connecter

Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.

Questions fréquentes

Can I take Carboplatin with Zidovudine?

MediHelp rates the interaction as major. Carboplatin and Zidovudine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents suppress the bone marrow, and combined use increases the risk of anemia, neutropenia and thrombocytopenia. Carboplatin is particularly myelosuppressive.

How serious is the interaction between Carboplatin and Zidovudine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor full blood counts frequently, and consider an alternative to zidovudine in patients on myelosuppressive chemotherapy. Reduce doses or provide growth factor support as needed.

What other medicines interact with Zidovudine?

MediHelp also lists interactions of Zidovudine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Stavudine, Atidarsagene autotemcel. The full list is on the Zidovudine page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Télécharger surApp Store Disponible surGoogle Play

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter