Interactions médicamenteuses
Cefaclor + Warfarin
Gravité: Modérée
Cefaclor and Warfarin: moderate interaction.
Dernière mise à jour
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Résumé
Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.
Ce que signifie cette interaction, en termes simples
Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefaclor belongs to Anti Bacterial; Warfarin belongs to Cardiovascular.
Pourquoi elle survient
Not firmly established; possibly reduced gut-derived vitamin K or other effects on warfarin response.
Conduite à tenir
Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefaclor
- Bcg vaccine live + Cefaclor Modérée
- Cefaclor + Cholera vaccine Modérée
- Cefaclor + Kanamycin Modérée
- Cefaclor + Microbiota Modérée
- Cefaclor + Plazomicin Modérée
- Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid Modérée
Autres interactions de Warfarin
- Defibrotide + Warfarin Contre-indiquée
- Ketorolac + Warfarin Contre-indiquée
- Abciximab + Warfarin Majeure
- Acetylsalicylic acid + Warfarin Majeure
- Adagrasib + Warfarin Majeure
- Amiodarone + Warfarin Majeure
Questions fréquentes
Can I take Cefaclor with Warfarin?
MediHelp rates the interaction as moderate. Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.
How serious is the interaction between Cefaclor and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
