Interactions médicamenteuses
Charcoal + Digoxin
Gravité: Modérée
Charcoal and Digoxin: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Activated charcoal adsorbs oral digoxin and interrupts its enterohepatic recirculation, lowering serum levels. This is helpful in digoxin toxicity but can reduce efficacy if given at therapeutic doses.
Ce que signifie cette interaction, en termes simples
Charcoal and Digoxin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Charcoal belongs to Gastrointestinal Tract; Digoxin belongs to Cardiovascular.
Pourquoi elle survient
Charcoal binds digoxin in the gut, decreasing absorption and enterohepatic recycling.
Conduite à tenir
Avoid charcoal in routine therapy or separate it from digoxin by several hours. In digoxin poisoning, charcoal is appropriate along with digoxin-specific antibody fragments and monitoring of levels and potassium.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Charcoal et Digoxin, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Charcoal
- Charcoal + Citalopram Modérée
- Charcoal + Leflunomide Modérée
- Charcoal + Methotrexate Modérée
- Charcoal + Theophylline Modérée
- Charcoal + Tiratricol Modérée
- Acarbose + Charcoal Mineure
Autres interactions de Digoxin
- Digoxin + Lily of the valley Contre-indiquée
- Digoxin + Squill Contre-indiquée
- Adagrasib + Digoxin Majeure
- Amiodarone + Digoxin Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Majeure
- Amphotericin b deoxycholate + Digoxin Majeure
Questions fréquentes
Can I take Charcoal with Digoxin?
MediHelp rates the interaction as moderate. Charcoal and Digoxin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal adsorbs oral digoxin and interrupts its enterohepatic recirculation, lowering serum levels. This is helpful in digoxin toxicity but can reduce efficacy if given at therapeutic doses.
How serious is the interaction between Charcoal and Digoxin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid charcoal in routine therapy or separate it from digoxin by several hours. In digoxin poisoning, charcoal is appropriate along with digoxin-specific antibody fragments and monitoring of levels and potassium.
What other medicines interact with Charcoal?
MediHelp also lists interactions of Charcoal with, for example, Citalopram, Leflunomide, Methotrexate. The full list is on the Charcoal page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
