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Interactions médicamenteuses

Cidofovir + Foscarnet

Gravité: Contre-indiquée

Cidofovir and Foscarnet: contraindicated interaction.

Dernière mise à jour Sources: US FDA label

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Résumé

Both agents are clearly nephrotoxic, and combined use markedly increases the risk of acute kidney injury. Cidofovir labeling contraindicates use with other nephrotoxic agents and requires a washout period after them.

Ce que signifie cette interaction, en termes simples

Cidofovir and Foscarnet are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Cidofovir belongs to Anti Virals; Foscarnet belongs to Anti Virals.

Niveau de preuve: High

Pourquoi elle survient

Additive direct renal tubular toxicity.

Conduite à tenir

Do not co-administer; choose an alternative antiviral strategy and, where sequential use is needed, allow an adequate washout with renal function monitoring.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Références

Questions fréquentes

Can I take Cidofovir with Foscarnet?

MediHelp rates the interaction as contraindicated. Cidofovir and Foscarnet are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents are clearly nephrotoxic, and combined use markedly increases the risk of acute kidney injury. Cidofovir labeling contraindicates use with other nephrotoxic agents and requires a washout period after them.

How serious is the interaction between Cidofovir and Foscarnet?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; choose an alternative antiviral strategy and, where sequential use is needed, allow an adequate washout with renal function monitoring.

What other medicines interact with Cidofovir?

MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.

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