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Interactions médicamenteuses

Ciprofloxacin + Ferrous fumarate

Gravité: Majeure

Ciprofloxacin and Ferrous fumarate: major interaction.

Dernière mise à jour

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Résumé

Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.

Ce que signifie cette interaction, en termes simples

Ciprofloxacin and Ferrous fumarate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ciprofloxacin belongs to Anti Bacterial; Ferrous fumarate belongs to Miscellaneous.

Niveau de preuve: High

Pourquoi elle survient

Ferrous iron chelates ciprofloxacin in the gastrointestinal tract, forming poorly absorbed complexes.

Conduite à tenir

Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ciprofloxacin with Ferrous fumarate?

MediHelp rates the interaction as major. Ciprofloxacin and Ferrous fumarate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.

How serious is the interaction between Ciprofloxacin and Ferrous fumarate?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.

What other medicines interact with Ciprofloxacin?

MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.

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