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Interactions médicamenteuses

Ciprofloxacin + Magnesium

Gravité: Majeure

Ciprofloxacin and Magnesium: major interaction.

Dernière mise à jour

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Résumé

Magnesium-containing products bind oral ciprofloxacin in the gut and markedly reduce its absorption. This can cause subtherapeutic antibiotic levels and treatment failure or resistance.

Ce que signifie cette interaction, en termes simples

Ciprofloxacin and Magnesium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ciprofloxacin belongs to Anti Bacterial; Magnesium belongs to Gastrointestinal Tract.

Niveau de preuve: High

Pourquoi elle survient

Magnesium cations chelate ciprofloxacin, forming poorly absorbed complexes.

Conduite à tenir

Give ciprofloxacin at least 2 hours before or 6 hours after magnesium products. Consider a non-chelating alternative if separation is not feasible.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ciprofloxacin with Magnesium?

MediHelp rates the interaction as major. Ciprofloxacin and Magnesium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium-containing products bind oral ciprofloxacin in the gut and markedly reduce its absorption. This can cause subtherapeutic antibiotic levels and treatment failure or resistance.

How serious is the interaction between Ciprofloxacin and Magnesium?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ciprofloxacin at least 2 hours before or 6 hours after magnesium products. Consider a non-chelating alternative if separation is not feasible.

What other medicines interact with Magnesium?

MediHelp also lists interactions of Magnesium with, for example, Pancuronium, Rocuronium, Vecuronium. The full list is on the Magnesium page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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