Aller au contenu
MediHelp
MediHelp Référence médicamenteuse

Interactions médicamenteuses

Cisapride + Citalopram

Gravité: Contre-indiquée

Cisapride and Citalopram: contraindicated interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Citalopram causes dose-related QT prolongation and cisapride has a well-known risk of ventricular arrhythmia. Together they increase the chance of torsades de pointes.

Ce que signifie cette interaction, en termes simples

Cisapride and Citalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Cisapride belongs to Gastrointestinal Tract; Citalopram belongs to Central Nervous System.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive prolongation of ventricular repolarization through hERG potassium channel inhibition.

Conduite à tenir

Avoid concurrent use and choose an alternative to cisapride or a less QT-active antidepressant such as sertraline. If unavoidable, monitor the ECG and keep potassium and magnesium normal.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Cisapride et Citalopram, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
Créer un compte gratuit Se connecter

Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.

Questions fréquentes

Can I take Cisapride with Citalopram?

MediHelp rates the interaction as contraindicated. Cisapride and Citalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Citalopram causes dose-related QT prolongation and cisapride has a well-known risk of ventricular arrhythmia. Together they increase the chance of torsades de pointes.

How serious is the interaction between Cisapride and Citalopram?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose an alternative to cisapride or a less QT-active antidepressant such as sertraline. If unavoidable, monitor the ECG and keep potassium and magnesium normal.

What other medicines interact with Cisapride?

MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Télécharger surApp Store Disponible surGoogle Play

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter