Interactions médicamenteuses
Clindamycin + Microbiota
Gravité: Majeure
Clindamycin and Microbiota: major interaction.
Dernière mise à jour
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Résumé
Oral fecal microbiota products contain live bacterial spores meant to re-establish the gut flora after Clostridioides difficile infection. Antibacterial agents active against these organisms can suppress engraftment and lower efficacy. Clindamycin has broad anaerobic activity and is itself a major risk factor for C. difficile.
Ce que signifie cette interaction, en termes simples
Clindamycin and Microbiota can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Antibacterial activity against the administered live bacterial spores and the resulting flora impairs engraftment and colonization.
Conduite à tenir
Complete any antibiotic course before starting the microbiota product, observing the interval in the product labeling. Avoid starting clindamycin during or soon after microbiota therapy unless clearly necessary.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Clindamycin
- Atracurium + Clindamycin Majeure
- Cisatracurium + Clindamycin Majeure
- Clindamycin + Pancuronium Majeure
- Clindamycin + Rapacuronium Majeure
- Clindamycin + Rocuronium Majeure
- Clindamycin + Vecuronium Majeure
Questions fréquentes
Can I take Clindamycin with Microbiota?
MediHelp rates the interaction as major. Clindamycin and Microbiota can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral fecal microbiota products contain live bacterial spores meant to re-establish the gut flora after Clostridioides difficile infection. Antibacterial agents active against these organisms can suppress engraftment and lower efficacy. Clindamycin has broad anaerobic activity and is itself a major risk factor for C. difficile.
How serious is the interaction between Clindamycin and Microbiota?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete any antibiotic course before starting the microbiota product, observing the interval in the product labeling. Avoid starting clindamycin during or soon after microbiota therapy unless clearly necessary.
What other medicines interact with Clindamycin?
MediHelp also lists interactions of Clindamycin with, for example, Atracurium, Cisatracurium, Pancuronium. The full list is on the Clindamycin page.
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