Interactions médicamenteuses
Copper + Penicillamine
Gravité: Modérée
Copper and Penicillamine: moderate interaction.
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Résumé
Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
Ce que signifie cette interaction, en termes simples
Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
Pourquoi elle survient
Pharmacodynamic antagonism, since penicillamine chelates copper and promotes its urinary excretion.
Conduite à tenir
Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Penicillamine
- Gold sodium thiomalate + Penicillamine Majeure
- Aluminum hydroxide + Penicillamine Modérée
- Calcium carbonate + Penicillamine Modérée
- Calcium + Penicillamine Modérée
- Carbonyl iron + Penicillamine Modérée
- Digoxin + Penicillamine Modérée
Autres interactions de Copper
- Copper + Omadacycline Modérée
- Copper + Sarecycline Modérée
- Copper + Trientine Modérée
- Ascorbic acid + Copper Mineure
- Baloxavir marboxil + Copper Mineure
- Copper + Vitamin c Mineure
Questions fréquentes
Can I take Copper with Penicillamine?
MediHelp rates the interaction as moderate. Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
How serious is the interaction between Copper and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
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