Interactions médicamenteuses
Carbonyl iron + Penicillamine
Gravité: Modérée
Carbonyl iron and Penicillamine: moderate interaction.
Dernière mise à jour
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Résumé
Oral iron binds penicillamine in the gut and can substantially reduce its absorption, which may lead to reduced therapeutic effect. Stopping iron can later increase penicillamine exposure.
Ce que signifie cette interaction, en termes simples
Carbonyl iron and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Penicillamine belongs to Musculoskeletal.
Pourquoi elle survient
Chelation of penicillamine by iron in the gastrointestinal tract reduces absorption.
Conduite à tenir
Separate doses by at least 2 hours, giving penicillamine on an empty stomach. Monitor clinical response and adjust the dose if iron is started or stopped.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Penicillamine
- Gold sodium thiomalate + Penicillamine Majeure
- Aluminum hydroxide + Penicillamine Modérée
- Calcium carbonate + Penicillamine Modérée
- Calcium + Penicillamine Modérée
- Copper + Penicillamine Modérée
- Digoxin + Penicillamine Modérée
Autres interactions de Carbonyl iron
Questions fréquentes
Can I take Carbonyl iron with Penicillamine?
MediHelp rates the interaction as moderate. Carbonyl iron and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron binds penicillamine in the gut and can substantially reduce its absorption, which may lead to reduced therapeutic effect. Stopping iron can later increase penicillamine exposure.
How serious is the interaction between Carbonyl iron and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours, giving penicillamine on an empty stomach. Monitor clinical response and adjust the dose if iron is started or stopped.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
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