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Interactions médicamenteuses

Dengue vaccine + Upadacitinib

Gravité: Contre-indiquée

Dengue vaccine and Upadacitinib: contraindicated interaction.

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Résumé

The dengue vaccine is live attenuated, and immunosuppression from upadacitinib may allow uncontrolled vaccine virus replication. The immune response may also be inadequate.

Ce que signifie cette interaction, en termes simples

Dengue vaccine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Low

Pourquoi elle survient

Immunosuppression impairs control of live attenuated virus and reduces vaccine response.

Conduite à tenir

Avoid the live dengue vaccine during upadacitinib treatment. Vaccinate before starting therapy where indicated.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Dengue vaccine with Upadacitinib?

MediHelp rates the interaction as contraindicated. Dengue vaccine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The dengue vaccine is live attenuated, and immunosuppression from upadacitinib may allow uncontrolled vaccine virus replication. The immune response may also be inadequate.

How serious is the interaction between Dengue vaccine and Upadacitinib?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live dengue vaccine during upadacitinib treatment. Vaccinate before starting therapy where indicated.

What other medicines interact with Upadacitinib?

MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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