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Interactions médicamenteuses

Desogestrel-ethinyl estradiol + Mineral oil

Gravité: Mineure

Desogestrel-ethinyl estradiol and Mineral oil: minor interaction.

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Résumé

Oral mineral oil may dissolve lipophilic drugs in the gut and reduce their absorption, which could lower contraceptive hormone exposure. Clinical evidence is lacking.

Ce que signifie cette interaction, en termes simples

Desogestrel-ethinyl estradiol and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Desogestrel-ethinyl estradiol belongs to Endocrine; Mineral oil belongs to Gastrointestinal Tract.

Niveau de preuve: Low

Pourquoi elle survient

Mineral oil sequesters lipophilic steroids in the intestinal lumen and reduces absorption.

Conduite à tenir

Separate administration by at least two hours and avoid regular use of mineral oil laxatives with the pill.

Questions à poser à votre pharmacien

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Desogestrel-ethinyl estradiol with Mineral oil?

MediHelp rates the interaction as minor. Desogestrel-ethinyl estradiol and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral mineral oil may dissolve lipophilic drugs in the gut and reduce their absorption, which could lower contraceptive hormone exposure. Clinical evidence is lacking.

How serious is the interaction between Desogestrel-ethinyl estradiol and Mineral oil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by at least two hours and avoid regular use of mineral oil laxatives with the pill.

What other medicines interact with Desogestrel-ethinyl estradiol?

MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.

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