Interactions médicamenteuses
Digoxin + Senna
Gravité: Modérée
Digoxin and Senna: moderate interaction.
Dernière mise à jour
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Résumé
Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
Ce que signifie cette interaction, en termes simples
Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Senna belongs to Gastrointestinal Tract.
Pourquoi elle survient
Laxative-induced gastrointestinal potassium loss produces hypokalemia, which enhances digoxin's cardiac toxicity.
Conduite à tenir
Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Digoxin
- Digoxin + Lily of the valley Contre-indiquée
- Digoxin + Squill Contre-indiquée
- Adagrasib + Digoxin Majeure
- Amiodarone + Digoxin Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Majeure
- Amphotericin b deoxycholate + Digoxin Majeure
Autres interactions de Senna
Questions fréquentes
Can I take Digoxin with Senna?
MediHelp rates the interaction as moderate. Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
How serious is the interaction between Digoxin and Senna?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
