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Interactions médicamenteuses

Droperidol + Moxifloxacin

Gravité: Contre-indiquée

Droperidol and Moxifloxacin: contraindicated interaction.

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Résumé

Droperidol carries a boxed warning for QT prolongation and torsades de pointes, and moxifloxacin adds to that effect. Co-administration substantially raises the arrhythmia risk.

Ce que signifie cette interaction, en termes simples

Droperidol and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive pharmacodynamic QT prolongation.

Conduite à tenir

Avoid the combination and use a non-QT-prolonging antiemetic or antibiotic. If unavoidable, obtain an ECG and monitor continuously.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Droperidol with Moxifloxacin?

MediHelp rates the interaction as contraindicated. Droperidol and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Droperidol carries a boxed warning for QT prolongation and torsades de pointes, and moxifloxacin adds to that effect. Co-administration substantially raises the arrhythmia risk.

How serious is the interaction between Droperidol and Moxifloxacin?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antiemetic or antibiotic. If unavoidable, obtain an ECG and monitor continuously.

What other medicines interact with Moxifloxacin?

MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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