Interactions médicamenteuses
Dulaglutide + Insulin degludec-liraglutide
Gravité: Majeure
Dulaglutide and Insulin degludec-liraglutide: major interaction.
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Résumé
Dulaglutide and liraglutide are both GLP-1 receptor agonists, so combining them duplicates therapy and increases gastrointestinal adverse effects and hypoglycemia risk without added benefit. The insulin component further contributes to hypoglycemia.
Ce que signifie cette interaction, en termes simples
Dulaglutide and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dulaglutide belongs to Endocrine; Insulin degludec-liraglutide belongs to Endocrine.
Pourquoi elle survient
Duplicate GLP-1 receptor agonism produces additive pharmacodynamic effects.
Conduite à tenir
Avoid using two GLP-1 receptor agonists together; use only one agent and stop the duplicate.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin degludec-liraglutide
- Albiglutide + Insulin degludec-liraglutide Majeure
- Chlorpropamide + Insulin degludec-liraglutide Majeure
- Clozapine + Insulin degludec-liraglutide Majeure
- Diazoxide + Insulin degludec-liraglutide Majeure
- Ethanol + Insulin degludec-liraglutide Majeure
- Exenatide injectable + Insulin degludec-liraglutide Majeure
Autres interactions de Dulaglutide
Questions fréquentes
Can I take Dulaglutide with Insulin degludec-liraglutide?
MediHelp rates the interaction as major. Dulaglutide and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dulaglutide and liraglutide are both GLP-1 receptor agonists, so combining them duplicates therapy and increases gastrointestinal adverse effects and hypoglycemia risk without added benefit. The insulin component further contributes to hypoglycemia.
How serious is the interaction between Dulaglutide and Insulin degludec-liraglutide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two GLP-1 receptor agonists together; use only one agent and stop the duplicate.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
