Interactions médicamenteuses
Exenatide injectable + Insulin degludec-liraglutide
Gravité: Majeure
Exenatide injectable and Insulin degludec-liraglutide: major interaction.
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Résumé
Exenatide is a GLP-1 receptor agonist, and the combination product already contains liraglutide, so the two would duplicate therapy. Together they increase gastrointestinal adverse effects and the risk of hypoglycemia without added benefit.
Ce que signifie cette interaction, en termes simples
Exenatide injectable and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Therapeutic duplication of GLP-1 receptor agonism with additive glucose-lowering effects.
Conduite à tenir
Avoid using two GLP-1 receptor agonists together. Use only one agent and adjust the insulin dose if switching.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin degludec-liraglutide
Questions fréquentes
Can I take Exenatide injectable with Insulin degludec-liraglutide?
MediHelp rates the interaction as major. Exenatide injectable and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Exenatide is a GLP-1 receptor agonist, and the combination product already contains liraglutide, so the two would duplicate therapy. Together they increase gastrointestinal adverse effects and the risk of hypoglycemia without added benefit.
How serious is the interaction between Exenatide injectable and Insulin degludec-liraglutide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two GLP-1 receptor agonists together. Use only one agent and adjust the insulin dose if switching.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
