Interactions médicamenteuses
Diazoxide + Insulin degludec-liraglutide
Gravité: Majeure
Diazoxide and Insulin degludec-liraglutide: major interaction.
Dernière mise à jour
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Résumé
Diazoxide causes hyperglycemia and directly opposes the glucose-lowering effect of insulin and liraglutide. Glycemic control can deteriorate substantially, sometimes with ketoacidosis in diabetic patients.
Ce que signifie cette interaction, en termes simples
Diazoxide and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Diazoxide belongs to Miscellaneous; Insulin degludec-liraglutide belongs to Endocrine.
Pourquoi elle survient
Diazoxide opens pancreatic beta-cell potassium channels, suppressing insulin secretion, and also raises catecholamines.
Conduite à tenir
Avoid the combination where possible. If it is used, monitor blood glucose closely and increase antidiabetic doses as needed.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin degludec-liraglutide
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- Ethanol + Insulin degludec-liraglutide Majeure
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Autres interactions de Diazoxide
Questions fréquentes
Can I take Diazoxide with Insulin degludec-liraglutide?
MediHelp rates the interaction as major. Diazoxide and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Diazoxide causes hyperglycemia and directly opposes the glucose-lowering effect of insulin and liraglutide. Glycemic control can deteriorate substantially, sometimes with ketoacidosis in diabetic patients.
How serious is the interaction between Diazoxide and Insulin degludec-liraglutide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible. If it is used, monitor blood glucose closely and increase antidiabetic doses as needed.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
