Interactions médicamenteuses
Empagliflozin-metformin + Entecavir
Gravité: Modérée
Empagliflozin-metformin and Entecavir: moderate interaction.
Dernière mise à jour
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Résumé
Entecavir carries a labeled warning for lactic acidosis, and metformin also carries this risk. Using both may add to the risk, particularly with renal impairment or hepatic disease.
Ce que signifie cette interaction, en termes simples
Empagliflozin-metformin and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Empagliflozin-metformin belongs to Endocrine; Entecavir belongs to Anti Virals.
Pourquoi elle survient
Additive risk of lactic acidosis, with entecavir possibly impairing mitochondrial function; no established pharmacokinetic interaction.
Conduite à tenir
Monitor renal and hepatic function and watch for symptoms of lactic acidosis such as malaise, myalgia and rapid breathing. Stop metformin if lactic acidosis is suspected.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Empagliflozin-metformin
Autres interactions de Entecavir
Questions fréquentes
Can I take Empagliflozin-metformin with Entecavir?
MediHelp rates the interaction as moderate. Empagliflozin-metformin and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Entecavir carries a labeled warning for lactic acidosis, and metformin also carries this risk. Using both may add to the risk, particularly with renal impairment or hepatic disease.
How serious is the interaction between Empagliflozin-metformin and Entecavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal and hepatic function and watch for symptoms of lactic acidosis such as malaise, myalgia and rapid breathing. Stop metformin if lactic acidosis is suspected.
What other medicines interact with Empagliflozin-metformin?
MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
