Interactions médicamenteuses
Cidofovir + Entecavir
Gravité: Modérée
Cidofovir and Entecavir: moderate interaction.
Dernière mise à jour
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Résumé
Both drugs are eliminated by the kidney including active tubular secretion, so they may raise each other's levels. Cidofovir's nephrotoxicity could further reduce entecavir clearance. The practical significance is uncertain.
Ce que signifie cette interaction, en termes simples
Cidofovir and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cidofovir belongs to Anti Virals; Entecavir belongs to Anti Virals.
Pourquoi elle survient
Competition for renal tubular secretion and cidofovir-related reduction in renal function.
Conduite à tenir
Monitor renal function and adjust the entecavir dose according to creatinine clearance if renal function worsens.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cidofovir
- Amikacin + Cidofovir Contre-indiquée
- Amphotericin b deoxycholate + Cidofovir Contre-indiquée
- Amphotericin b + Cidofovir Contre-indiquée
- Bacitracin + Cidofovir Contre-indiquée
- Capreomycin + Cidofovir Contre-indiquée
- Cephaloridine + Cidofovir Contre-indiquée
Autres interactions de Entecavir
Questions fréquentes
Can I take Cidofovir with Entecavir?
MediHelp rates the interaction as moderate. Cidofovir and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidney including active tubular secretion, so they may raise each other's levels. Cidofovir's nephrotoxicity could further reduce entecavir clearance. The practical significance is uncertain.
How serious is the interaction between Cidofovir and Entecavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and adjust the entecavir dose according to creatinine clearance if renal function worsens.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
