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Interactions médicamenteuses

Ethinyl estradiol-norgestimate + Mineral oil

Gravité: Mineure

Ethinyl estradiol-norgestimate and Mineral oil: minor interaction.

Dernière mise à jour

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Résumé

Oral mineral oil may dissolve fat-soluble substances in the gut and reduce absorption of lipophilic steroid hormones. In theory this could lower contraceptive hormone exposure, though clinical significance is uncertain with occasional use.

Ce que signifie cette interaction, en termes simples

Ethinyl estradiol-norgestimate and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Ethinyl estradiol-norgestimate belongs to Endocrine; Mineral oil belongs to Gastrointestinal Tract.

Niveau de preuve: Low

Pourquoi elle survient

Mineral oil acts as a lipid solvent in the intestinal lumen, which may reduce absorption of lipophilic drugs.

Conduite à tenir

Avoid regular use of mineral oil and take the contraceptive at least 2 hours before or after any dose. Counsel the patient to use backup contraception if prolonged diarrhea or heavy laxative use occurs.

Questions à poser à votre pharmacien

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ethinyl estradiol-norgestimate with Mineral oil?

MediHelp rates the interaction as minor. Ethinyl estradiol-norgestimate and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral mineral oil may dissolve fat-soluble substances in the gut and reduce absorption of lipophilic steroid hormones. In theory this could lower contraceptive hormone exposure, though clinical significance is uncertain with occasional use.

How serious is the interaction between Ethinyl estradiol-norgestimate and Mineral oil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use of mineral oil and take the contraceptive at least 2 hours before or after any dose. Counsel the patient to use backup contraception if prolonged diarrhea or heavy laxative use occurs.

What other medicines interact with Ethinyl estradiol-norgestimate?

MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-norgestimate page.

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