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Interactions médicamenteuses

Famciclovir + Raloxifene

Gravité: Mineure

Famciclovir and Raloxifene: minor interaction.

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Résumé

Famciclovir is a prodrug that is converted to its active form, penciclovir, partly through aldehyde oxidase. Raloxifene inhibits this enzyme in vitro, so it could lower penciclovir formation and reduce antiviral effect. The clinical relevance in patients has not been shown.

Ce que signifie cette interaction, en termes simples

Famciclovir and Raloxifene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Famciclovir belongs to Anti Virals; Raloxifene belongs to Endocrine.

Niveau de preuve: Low

Pourquoi elle survient

Raloxifene inhibits aldehyde oxidase in vitro, which may reduce conversion of 6-deoxypenciclovir to penciclovir.

Conduite à tenir

No routine change is needed. If an infection responds poorly to famciclovir in a patient taking raloxifene, consider this interaction and review the antiviral choice or dose.

Questions à poser à votre pharmacien

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Famciclovir with Raloxifene?

MediHelp rates the interaction as minor. Famciclovir and Raloxifene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Famciclovir is a prodrug that is converted to its active form, penciclovir, partly through aldehyde oxidase. Raloxifene inhibits this enzyme in vitro, so it could lower penciclovir formation and reduce antiviral effect. The clinical relevance in patients has not been shown.

How serious is the interaction between Famciclovir and Raloxifene?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. If an infection responds poorly to famciclovir in a patient taking raloxifene, consider this interaction and review the antiviral choice or dose.

What other medicines interact with Raloxifene?

MediHelp also lists interactions of Raloxifene with, for example, Cholestyramine, Ospemifene, Apalutamide. The full list is on the Raloxifene page.

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