Interactions médicamenteuses
Insulin aspart protamine / insulin aspart + Rosiglitazone
Gravité: Majeure
Insulin aspart protamine / insulin aspart and Rosiglitazone: major interaction.
Dernière mise à jour
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Résumé
Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
Ce que signifie cette interaction, en termes simples
Insulin aspart protamine / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive glucose-lowering effects, and combined sodium and fluid retention from thiazolidinedione and insulin.
Conduite à tenir
Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Rosiglitazone
- Insulin aspart-insulin aspart protamine + Rosiglitazone Majeure
- Insulin aspart + Rosiglitazone Majeure
- Insulin degludec / insulin aspart + Rosiglitazone Majeure
- Insulin degludec-insulin aspart + Rosiglitazone Majeure
- Insulin degludec-liraglutide + Rosiglitazone Majeure
- Insulin degludec + Rosiglitazone Majeure
Questions fréquentes
Can I take Insulin aspart protamine / insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin aspart protamine / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
How serious is the interaction between Insulin aspart protamine / insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart-insulin aspart protamine, Insulin aspart, Insulin degludec / insulin aspart. The full list is on the Rosiglitazone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
