Interactions médicamenteuses
Insulin aspart + Rosiglitazone
Gravité: Majeure
Insulin aspart and Rosiglitazone: major interaction.
Dernière mise à jour
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Résumé
Rosiglitazone with insulin increases the risk of edema, heart failure and possibly ischemic cardiac events, and the glucose-lowering effects are additive. Hypoglycemia may occur.
Ce que signifie cette interaction, en termes simples
Insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin aspart belongs to Endocrine; Rosiglitazone belongs to Endocrine.
Pourquoi elle survient
PPAR-gamma-mediated renal sodium and fluid retention compounded by insulin, plus additive glucose lowering.
Conduite à tenir
Monitor for edema, rapid weight gain and heart failure symptoms; avoid in patients with heart failure. Reduce the insulin dose if hypoglycemia occurs.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin aspart
Autres interactions de Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Majeure
- Insulin aspart-insulin aspart protamine + Rosiglitazone Majeure
- Insulin degludec / insulin aspart + Rosiglitazone Majeure
- Insulin degludec-insulin aspart + Rosiglitazone Majeure
- Insulin degludec-liraglutide + Rosiglitazone Majeure
- Insulin degludec + Rosiglitazone Majeure
Questions fréquentes
Can I take Insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin increases the risk of edema, heart failure and possibly ischemic cardiac events, and the glucose-lowering effects are additive. Hypoglycemia may occur.
How serious is the interaction between Insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for edema, rapid weight gain and heart failure symptoms; avoid in patients with heart failure. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin aspart?
MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
