Interactions médicamenteuses
Insulin degludec-insulin aspart + Rosiglitazone
Gravité: Majeure
Insulin degludec-insulin aspart and Rosiglitazone: major interaction.
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Résumé
Rosiglitazone combined with insulin increases glucose lowering and the risk of hypoglycemia. The combination markedly raises the risk of edema and heart failure, and labeling advises against its use with insulin.
Ce que signifie cette interaction, en termes simples
Insulin degludec-insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec-insulin aspart belongs to Endocrine; Rosiglitazone belongs to Endocrine.
Pourquoi elle survient
Rosiglitazone increases insulin sensitivity and causes fluid retention, adding to insulin effect and cardiac volume load.
Conduite à tenir
Avoid combining where possible; if used, reduce insulin as needed and monitor for edema, weight gain and heart failure.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Majeure
- Clozapine + Insulin degludec-insulin aspart Majeure
- Diazoxide + Insulin degludec-insulin aspart Majeure
- Ethanol + Insulin degludec-insulin aspart Majeure
- Insulin degludec-insulin aspart + Mecasermin Majeure
- Insulin degludec-insulin aspart + Pioglitazone Majeure
Autres interactions de Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Majeure
- Insulin aspart-insulin aspart protamine + Rosiglitazone Majeure
- Insulin aspart + Rosiglitazone Majeure
- Insulin degludec / insulin aspart + Rosiglitazone Majeure
- Insulin degludec-liraglutide + Rosiglitazone Majeure
- Insulin degludec + Rosiglitazone Majeure
Questions fréquentes
Can I take Insulin degludec-insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec-insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone combined with insulin increases glucose lowering and the risk of hypoglycemia. The combination markedly raises the risk of edema and heart failure, and labeling advises against its use with insulin.
How serious is the interaction between Insulin degludec-insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; if used, reduce insulin as needed and monitor for edema, weight gain and heart failure.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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