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Interactions médicamenteuses

Moxifloxacin + Strontium ranelate

Gravité: Modérée

Moxifloxacin and Strontium ranelate: moderate interaction.

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Résumé

Oral strontium ranelate can bind moxifloxacin in the gut and reduce its absorption, which may lead to subtherapeutic antibiotic concentrations and treatment failure. The effect is relevant only when both are taken by mouth.

Ce que signifie cette interaction, en termes simples

Moxifloxacin and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Moxifloxacin belongs to Anti Bacterial; Strontium ranelate belongs to Musculoskeletal.

Niveau de preuve: Moderate

Pourquoi elle survient

Chelation of the fluoroquinolone by divalent strontium cations in the gastrointestinal tract, reducing absorption.

Conduite à tenir

Interrupt strontium ranelate for the duration of oral moxifloxacin therapy. If it cannot be stopped, separate doses widely and watch for clinical response.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Moxifloxacin with Strontium ranelate?

MediHelp rates the interaction as moderate. Moxifloxacin and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral strontium ranelate can bind moxifloxacin in the gut and reduce its absorption, which may lead to subtherapeutic antibiotic concentrations and treatment failure. The effect is relevant only when both are taken by mouth.

How serious is the interaction between Moxifloxacin and Strontium ranelate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interrupt strontium ranelate for the duration of oral moxifloxacin therapy. If it cannot be stopped, separate doses widely and watch for clinical response.

What other medicines interact with Moxifloxacin?

MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.

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