दवाओं की अंतःक्रिया
Alfentanil + Diphenoxylate-atropine
गंभीरता: गंभीर
Alfentanil and Diphenoxylate-atropine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Diphenoxylate is an opioid, and together with alfentanil it can increase sedation and respiratory depression. Risk is higher at high diphenoxylate doses or in children and those with hepatic impairment.
इस इंटरैक्शन का सरल भाषा में अर्थ
Alfentanil and Diphenoxylate-atropine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Additive opioid-mediated CNS and respiratory depression.
क्या करें
Monitor respiratory rate and sedation level during alfentanil use and reduce the alfentanil dose as needed. Hold diphenoxylate-atropine where possible around procedures.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Alfentanil और Diphenoxylate-atropine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Diphenoxylate-atropine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Alfentanil with Diphenoxylate-atropine?
MediHelp rates the interaction as major. Alfentanil and Diphenoxylate-atropine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Diphenoxylate is an opioid, and together with alfentanil it can increase sedation and respiratory depression. Risk is higher at high diphenoxylate doses or in children and those with hepatic impairment.
How serious is the interaction between Alfentanil and Diphenoxylate-atropine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory rate and sedation level during alfentanil use and reduce the alfentanil dose as needed. Hold diphenoxylate-atropine where possible around procedures.
What other medicines interact with Diphenoxylate-atropine?
MediHelp also lists interactions of Diphenoxylate-atropine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Diphenoxylate-atropine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
