दवाओं की अंतःक्रिया
Diphenoxylate-atropine + Isocarboxazid
गंभीरता: निषिद्ध
Diphenoxylate-atropine and Isocarboxazid: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Diphenoxylate is structurally related to meperidine, and MAO inhibitors can cause severe reactions with such opioids. Hypertensive crisis, hyperpyrexia, hypotension, somnolence or death may occur. Labeling advises against use of diphenoxylate with MAO inhibitors.
इस इंटरैक्शन का सरल भाषा में अर्थ
Diphenoxylate-atropine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Diphenoxylate-atropine belongs to Gastrointestinal Tract; Isocarboxazid belongs to Central Nervous System.
ऐसा क्यों होता है
MAO inhibition may potentiate diphenoxylate through a meperidine-like interaction; the exact mechanism is not fully established.
क्या करें
Do not use together or within 14 days of stopping the MAO inhibitor. Use a non-opioid antidiarrheal alternative.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Diphenoxylate-atropine और Isocarboxazid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Diphenoxylate-atropine के अन्य इंटरैक्शन
Isocarboxazid के अन्य इंटरैक्शन
- 5-HTP + Isocarboxazid निषिद्ध
- Amitriptyline + Isocarboxazid निषिद्ध
- Amobarbital + Isocarboxazid निषिद्ध
- Amoxapine + Isocarboxazid निषिद्ध
- Apraclonidine + Isocarboxazid निषिद्ध
- Atomoxetine + Isocarboxazid निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Diphenoxylate-atropine with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Diphenoxylate-atropine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Diphenoxylate is structurally related to meperidine, and MAO inhibitors can cause severe reactions with such opioids. Hypertensive crisis, hyperpyrexia, hypotension, somnolence or death may occur. Labeling advises against use of diphenoxylate with MAO inhibitors.
How serious is the interaction between Diphenoxylate-atropine and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 14 days of stopping the MAO inhibitor. Use a non-opioid antidiarrheal alternative.
What other medicines interact with Diphenoxylate-atropine?
MediHelp also lists interactions of Diphenoxylate-atropine with, for example, Phenelzine, Tranylcypromine, Alfentanil. The full list is on the Diphenoxylate-atropine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
