दवाओं की अंतःक्रिया
Diphenoxylate-atropine + Tranylcypromine
गंभीरता: निषिद्ध
Diphenoxylate-atropine and Tranylcypromine: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Diphenoxylate is labeled as potentially causing hypertensive crisis when given with MAO inhibitors. Tranylcypromine is a nonselective irreversible MAOI, so the risk of severe hypertension and agitation is substantial.
इस इंटरैक्शन का सरल भाषा में अर्थ
Diphenoxylate-atropine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Diphenoxylate-atropine belongs to Gastrointestinal Tract; Tranylcypromine belongs to Central Nervous System.
ऐसा क्यों होता है
Irreversible MAO inhibition may potentiate the pressor and CNS effects of the opioid; the exact mechanism is not fully defined.
क्या करें
Do not co-administer, and do not start diphenoxylate-atropine within 14 days of stopping tranylcypromine. Use a different antidiarrheal such as loperamide.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Diphenoxylate-atropine और Tranylcypromine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Diphenoxylate-atropine के अन्य इंटरैक्शन
Tranylcypromine के अन्य इंटरैक्शन
- 5-HTP + Tranylcypromine निषिद्ध
- Amitriptyline + Tranylcypromine निषिद्ध
- Amoxapine + Tranylcypromine निषिद्ध
- Atomoxetine + Tranylcypromine निषिद्ध
- Benzphetamine + Tranylcypromine निषिद्ध
- Brimonidine + Tranylcypromine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Diphenoxylate-atropine with Tranylcypromine?
MediHelp rates the interaction as contraindicated. Diphenoxylate-atropine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Diphenoxylate is labeled as potentially causing hypertensive crisis when given with MAO inhibitors. Tranylcypromine is a nonselective irreversible MAOI, so the risk of severe hypertension and agitation is substantial.
How serious is the interaction between Diphenoxylate-atropine and Tranylcypromine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer, and do not start diphenoxylate-atropine within 14 days of stopping tranylcypromine. Use a different antidiarrheal such as loperamide.
What other medicines interact with Diphenoxylate-atropine?
MediHelp also lists interactions of Diphenoxylate-atropine with, for example, Isocarboxazid, Phenelzine, Alfentanil. The full list is on the Diphenoxylate-atropine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
