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दवाओं की अंतःक्रिया

Chloramphenicol + Erdafitinib

गंभीरता: गंभीर

Chloramphenicol and Erdafitinib: major interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Erdafitinib is metabolized by CYP2C9 and CYP3A4, and inhibition of these pathways can raise its exposure. This may increase hyperphosphatemia, ocular and dermatologic toxicity, and stomatitis.

इस इंटरैक्शन का सरल भाषा में अर्थ

Chloramphenicol and Erdafitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Chloramphenicol belongs to Anti Bacterial; Erdafitinib belongs to Oncology.

साक्ष्य स्तर: Low

ऐसा क्यों होता है

Chloramphenicol inhibits CYP3A4 and CYP2C9, reducing erdafitinib clearance.

क्या करें

Use an alternative antibiotic if possible. If coadministered, monitor closely for adverse reactions and consider reducing the erdafitinib dose, and re-escalate after the inhibitor is stopped if no toxicity.

फार्मासिस्ट से क्या पूछें

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Chloramphenicol और Erdafitinib की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Chloramphenicol with Erdafitinib?

MediHelp rates the interaction as major. Chloramphenicol and Erdafitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Erdafitinib is metabolized by CYP2C9 and CYP3A4, and inhibition of these pathways can raise its exposure. This may increase hyperphosphatemia, ocular and dermatologic toxicity, and stomatitis.

How serious is the interaction between Chloramphenicol and Erdafitinib?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use an alternative antibiotic if possible. If coadministered, monitor closely for adverse reactions and consider reducing the erdafitinib dose, and re-escalate after the inhibitor is stopped if no toxicity.

What other medicines interact with Chloramphenicol?

MediHelp also lists interactions of Chloramphenicol with, for example, Adagrasib, Avapritinib, Bcg vaccine live. The full list is on the Chloramphenicol page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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