दवाओं की अंतःक्रिया
Domperidone + Omeprazole
गंभीरता: हल्की
Domperidone and Omeprazole: minor interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Reduced gastric acidity from omeprazole may lower the absorption of domperidone, which needs an acidic environment for dissolution. This may reduce the prokinetic or antiemetic effect. The clinical impact is usually modest, and omeprazole does not meaningfully inhibit CYP3A4 or add to QT risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Domperidone and Omeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Domperidone belongs to Gastrointestinal Tract; Omeprazole belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Higher gastric pH from proton pump inhibition reduces domperidone dissolution and absorption. It is not mediated through CYP3A4.
क्या करें
Give domperidone 15 to 30 minutes before meals as labelled. Review clinical response and adjust therapy if efficacy is reduced.
फार्मासिस्ट से क्या पूछें
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Domperidone और Omeprazole की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
- Motilium (domperidone) Summary of Product Characteristics — EMA SmPC
Domperidone के अन्य इंटरैक्शन
Omeprazole के अन्य इंटरैक्शन
- Mavacamten + Omeprazole निषिद्ध
- Omeprazole + Rilpivirine निषिद्ध
- Acalabrutinib + Omeprazole गंभीर
- Atazanavir + Omeprazole गंभीर
- Citalopram + Omeprazole गंभीर
- Clopidogrel + Omeprazole गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Domperidone with Omeprazole?
MediHelp rates the interaction as minor. Domperidone and Omeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced gastric acidity from omeprazole may lower the absorption of domperidone, which needs an acidic environment for dissolution. This may reduce the prokinetic or antiemetic effect. The clinical impact is usually modest, and omeprazole does not meaningfully inhibit CYP3A4 or add to QT risk.
How serious is the interaction between Domperidone and Omeprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give domperidone 15 to 30 minutes before meals as labelled. Review clinical response and adjust therapy if efficacy is reduced.
What other medicines interact with Domperidone?
MediHelp also lists interactions of Domperidone with, for example, Azithromycin, Erythromycin, Dexlansoprazole. The full list is on the Domperidone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
