दवाओं की अंतःक्रिया
Glycerol phenylbutyrate + Hydrocortisone
गंभीरता: मध्यम
Glycerol phenylbutyrate and Hydrocortisone: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Corticosteroids promote protein catabolism, which can raise plasma ammonia. This opposes the ammonia-lowering goal of glycerol phenylbutyrate in urea cycle disorders and risks hyperammonemia.
इस इंटरैक्शन का सरल भाषा में अर्थ
Glycerol phenylbutyrate and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glycerol phenylbutyrate belongs to Miscellaneous; Hydrocortisone belongs to Endocrine.
ऐसा क्यों होता है
Corticosteroid-induced protein breakdown increases nitrogen load and ammonia production, counteracting nitrogen scavenging.
क्या करें
Monitor plasma ammonia closely when starting, stopping or changing hydrocortisone dose. Adjust glycerol phenylbutyrate and dietary protein as advised by the metabolic team.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Glycerol phenylbutyrate और Hydrocortisone की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Hydrocortisone के अन्य इंटरैक्शन
Glycerol phenylbutyrate के अन्य इंटरैक्शन
- Dexamethasone + Glycerol phenylbutyrate गंभीर
- Glycerol phenylbutyrate + Sodium valproate गंभीर
- Glycerol phenylbutyrate + Valproic acid गंभीर
- Cyclosporin + Glycerol phenylbutyrate मध्यम
- Dexamethasone-neomycin-polymyxin + Glycerol phenylbutyrate मध्यम
- Dexamethasone-tobramycin + Glycerol phenylbutyrate मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Glycerol phenylbutyrate with Hydrocortisone?
MediHelp rates the interaction as moderate. Glycerol phenylbutyrate and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids promote protein catabolism, which can raise plasma ammonia. This opposes the ammonia-lowering goal of glycerol phenylbutyrate in urea cycle disorders and risks hyperammonemia.
How serious is the interaction between Glycerol phenylbutyrate and Hydrocortisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor plasma ammonia closely when starting, stopping or changing hydrocortisone dose. Adjust glycerol phenylbutyrate and dietary protein as advised by the metabolic team.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Smallpox vaccine live. The full list is on the Hydrocortisone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
