दवाओं की अंतःक्रिया
Lidocaine + Pefloxacin
गंभीरता: मध्यम
Lidocaine and Pefloxacin: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Fluoroquinolones that inhibit CYP1A2 can reduce lidocaine clearance and raise its concentrations. Pefloxacin is a CYP1A2 inhibitor and this may lead to lidocaine toxicity with systemic or repeated dosing.
इस इंटरैक्शन का सरल भाषा में अर्थ
Lidocaine and Pefloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lidocaine belongs to Cardiovascular; Pefloxacin belongs to Anti Bacterial.
ऐसा क्यों होता है
Inhibition of CYP1A2-mediated lidocaine metabolism reduces clearance.
क्या करें
With systemic lidocaine infusion, monitor for signs of toxicity and consider dose reduction; no change is usually needed for single local anesthetic doses.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Lidocaine और Pefloxacin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Lidocaine के अन्य इंटरैक्शन
- Bupivacaine liposome + Lidocaine गंभीर
- Disopyramide + Lidocaine गंभीर
- Ex vivo expanded autologous human corneal epithelial cells containing stem cells + Lidocaine गंभीर
- Lidocaine + Nirmatrelvir / ritonavir गंभीर
- Lidocaine + Ombitasvir / paritaprevir / ritonavir and dasabuvir गंभीर
- Lidocaine + Pimozide गंभीर
Pefloxacin के अन्य इंटरैक्शन
- Pefloxacin + Tizanidine निषिद्ध
- Clozapine + Pefloxacin गंभीर
- Duloxetine + Pefloxacin गंभीर
- Pefloxacin + Theophylline गंभीर
- Asenapine + Pefloxacin मध्यम
- Caffeine + Pefloxacin मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Lidocaine with Pefloxacin?
MediHelp rates the interaction as moderate. Lidocaine and Pefloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fluoroquinolones that inhibit CYP1A2 can reduce lidocaine clearance and raise its concentrations. Pefloxacin is a CYP1A2 inhibitor and this may lead to lidocaine toxicity with systemic or repeated dosing.
How serious is the interaction between Lidocaine and Pefloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: With systemic lidocaine infusion, monitor for signs of toxicity and consider dose reduction; no change is usually needed for single local anesthetic doses.
What other medicines interact with Lidocaine?
MediHelp also lists interactions of Lidocaine with, for example, Bupivacaine liposome, Disopyramide, Ex vivo expanded autologous human corneal epithelial cells containing stem cells. The full list is on the Lidocaine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
