Riferimento farmaci
Dronabinol
Dronabinol is a medicine in the class central nervous system. It is used for nausea & vomiting.
- Classe del farmaco: Central Nervous System
- Indicato per: nausea & vomiting
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Central Nervous System
- Forme farmaceutiche comuni
- capsula, soluzione
- Dosaggi comuni
- 5 mg, 5 mg/ml
- Interazioni note
- 109 (Controindicata: 2 · Maggiore: 2 · Moderata: 75 · Minore: 30)
- Nomi commerciali
- 3
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Dronabinol is an orally active cannabinoid which has complex effects on the CNS, including central sympathomimetic activity. Cannabinoid receptors have been discovered in neural tissues; these receptors may play a role in mediating the effects of dronabinol. Has appetite stimulant effect
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Oral capsules: 5 mg/m² PO 1-3 hr before and q2-4hr after chemotherapy; may be increased in 2.5 mg/m² increments to 15 mg/m²; not to exceed 4-6 doses/day
Gravidanza e allattamento
- Gravidanza
- Unsafe May cause fetal harm; avoid use during pregnancy
- Allattamento
- Unsafe Use in nursing mothers is not recommended. Comments: -This drug is absorbed by the nursing infant. There are limited data on the effects on the nursing infant.
Effetti indesiderati segnalati
- Paranoid reaction
- Abnormal thinking
- Somnolence
- Abdominal Pain
- Dizziness
- Euphoria
Chi deve prestare attenzione
- Avoid concomitant use of drugs with similar effects and monitor for hemodynamic changes; monitor patients for changes in blood pressure, heart rate, and syncope after initiating or increasing the dosage (eg, amphetamines, other sympathomimetic agents, atropine, amoxapine, scopolamine, antihistamines, other anticholinergic agents, amitriptyline, etc
- Seizures and seizure-like activity reported
- New or worsening nausea, vomiting, or abdominal pain can occur during treatment with synthetic delta-9 tetrahydrocannabinol (delta-9-THC), the active ingredient in dronabinol
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Interazioni principali (109)
- Cefotetan + Dronabinol Contraindicated
- Disulfiram + Dronabinol Contraindicated
- Dronabinol + Midazolam intranasal Major
- Dronabinol + Zuranolone Major
- Amobarbital + Dronabinol Moderate
- Apalutamide + Dronabinol Moderate
- Atazanavir + Dronabinol Moderate
- Butabarbital + Dronabinol Moderate
- Butalbital + Dronabinol Moderate
- Cannabidiol + Dronabinol Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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Domande frequenti
What is Dronabinol used for?
Dronabinol is a medicine in the class central nervous system. It is used for Nausea & vomiting.
What side effects have been reported with Dronabinol?
Paranoid reaction, Abnormal thinking, Somnolence, Abdominal Pain, Dizziness, Euphoria.
Can Dronabinol be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm; avoid use during pregnancy Breastfeeding: Unsafe. Use in nursing mothers is not recommended. Comments: -This drug is absorbed by the nursing infant. There are limited data on the effects on the nursing infant.
What does Dronabinol interact with?
MediHelp lists 109 known interactions for Dronabinol. Contraindicated: 2 · Major: 2 · Moderate: 75 · Minor: 30. The most serious include Cefotetan, Disulfiram, Midazolam intranasal.
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