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Interazioni tra farmaci

Cefotetan + Dronabinol

Gravità: Controindicata

Cefotetan and Dronabinol: contraindicated interaction.

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Sintesi

Dronabinol oral solution contains a large amount of ethanol, and cefotetan can cause disulfiram-like reactions with alcohol. Flushing, nausea, vomiting, tachycardia and hypotension may result.

Cosa significa questa interazione in parole semplici

Cefotetan and Dronabinol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Cefotetan belongs to Anti Bacterial; Dronabinol belongs to Central Nervous System.

Livello di evidenza: Moderate

Perché avviene

Cefotetan inhibits aldehyde dehydrogenase, causing acetaldehyde accumulation from the ethanol in the dronabinol solution.

Cosa fare

Do not use dronabinol oral solution with cefotetan or within several days of either drug. Use dronabinol capsules or another antiemetic if cefotetan is needed.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Cefotetan with Dronabinol?

MediHelp rates the interaction as contraindicated. Cefotetan and Dronabinol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronabinol oral solution contains a large amount of ethanol, and cefotetan can cause disulfiram-like reactions with alcohol. Flushing, nausea, vomiting, tachycardia and hypotension may result.

How serious is the interaction between Cefotetan and Dronabinol?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use dronabinol oral solution with cefotetan or within several days of either drug. Use dronabinol capsules or another antiemetic if cefotetan is needed.

What other medicines interact with Dronabinol?

MediHelp also lists interactions of Dronabinol with, for example, Disulfiram, Midazolam intranasal, Zuranolone. The full list is on the Dronabinol page.

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