Interazioni tra farmaci
Atazanavir + Dronabinol
Gravità: Moderata
Atazanavir and Dronabinol: moderate interaction.
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Sintesi
Atazanavir inhibits CYP3A4 and may raise dronabinol concentrations. This can increase psychoactive and cardiovascular effects such as tachycardia, dizziness, anxiety and sedation.
Cosa significa questa interazione in parole semplici
Atazanavir and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Dronabinol belongs to Central Nervous System.
Perché avviene
Inhibition of CYP3A4-mediated dronabinol metabolism.
Cosa fare
Monitor for excessive CNS effects, tachycardia and hypotension, and lower the dronabinol dose if these occur.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Dronabinol
- Cefotetan + Dronabinol Controindicata
- Disulfiram + Dronabinol Controindicata
- Dronabinol + Midazolam intranasal Maggiore
- Dronabinol + Zuranolone Maggiore
- Amobarbital + Dronabinol Moderata
- Apalutamide + Dronabinol Moderata
Altre interazioni di Atazanavir
- Alfuzosin + Atazanavir Controindicata
- Atazanavir + Avanafil Controindicata
- Atazanavir + Dronedarone Controindicata
- Atazanavir + Eletriptan Controindicata
- Atazanavir + Eplerenone Controindicata
- Atazanavir + Ergotamine Controindicata
Domande frequenti
Can I take Atazanavir with Dronabinol?
MediHelp rates the interaction as moderate. Atazanavir and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir inhibits CYP3A4 and may raise dronabinol concentrations. This can increase psychoactive and cardiovascular effects such as tachycardia, dizziness, anxiety and sedation.
How serious is the interaction between Atazanavir and Dronabinol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive CNS effects, tachycardia and hypotension, and lower the dronabinol dose if these occur.
What other medicines interact with Dronabinol?
MediHelp also lists interactions of Dronabinol with, for example, Cefotetan, Disulfiram, Midazolam intranasal. The full list is on the Dronabinol page.
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