Riferimento farmaci
Miltefosine
Miltefosine is a medicine in the class anti parasitic. It is used for leishmaniasis.
- Classe del farmaco: Anti Parasitic
- Indicato per: leishmaniasis
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Anti Parasitic
- Forme farmaceutiche comuni
- capsula
- Dosaggi comuni
- 50 mg
- Nomi commerciali
- 2
- Paesi e mercati
- 1
Per cosa si usa
Come agisce
Miltefosine is an anti-leishmanial agent.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Visceral, cutaneous and mucosal leishmaniasis, weight 30 kg to 44 kg: one 50 mg capsule orally twice daily with food (breakfast and dinner) for 28 consecutive days
Gravidanza e allattamento
- Gravidanza
- Unsafe Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing.
- Allattamento
- Unsafe Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
Effetti indesiderati segnalati
- Vomiting
- Nausea
- Diarrhea
- Decreased appetite
- Headache
- Dizziness
Avvertenze in evidenza
- Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose. Do not give to pregnant women. Obtain a serum or urine pregnancy test in females of reproductive potential before prescribing. Advise effective contraception during therapy and for 5 months after therapy.
Controindicazioni
- Pregnancy
- Sjögren-Larsson-Syndrome
- Hypersensitivity to miltefosine or any of its excipients
Chi deve prestare attenzione
- Reproductive effects: testicular atrophy and impaired fertility in male rats and impaired fertility in female rats; effects on human fertility not adequately evaluated.
- Renal effects: serum creatinine elevations; monitor renal function weekly during therapy and for 4 weeks after.
- Hepatic effects: monitor ALT, AST and bilirubin during therapy.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Miltefosine used for?
Miltefosine is a medicine in the class anti parasitic. It is used for Leishmaniasis.
What side effects have been reported with Miltefosine?
Vomiting, Nausea, Diarrhea, Decreased appetite, Headache, Dizziness. Serious warning: Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose.
Can Miltefosine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing. Breastfeeding: Unsafe. Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
What does Miltefosine interact with?
MediHelp does not list a checked interaction for Miltefosine yet. Always tell your pharmacist about every medicine you take.
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