Riferimento farmaci
Scopolamine
Scopolamine is a medicine in the class respiratory. It is used for irritable bowel syndrome.
- Classe del farmaco: Respiratory
- Indicato per: irritable bowel syndrome
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Respiratory
- Forme farmaceutiche comuni
- cerotto, compressa
- Dosaggi comuni
- 10 mg, 5 mg/5 ml, 1 mg
- Interazioni note
- 143 (Maggiore: 17 · Moderata: 105 · Minore: 21)
- Nomi commerciali
- 19
- Paesi e mercati
- 3
Per cosa si usa
Come agisce
Its anticholinergic action exerts a smooth-muscle relaxing/spasmolytic effect. Blockade of the muscarinic receptors in the GI tract is the basis for its use in the treatment of abdominal pain secondary to cramping. Hyoscine butylbromide also binds to nicotinic receptors, which induces a ganglion-blocking effect.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Nausea & Vomiting (Treatment): 0.3-0.65 mg IV/IM/SC; repeat q6-8hr if necessary
Gravidanza e allattamento
- Gravidanza
- Unknown Covers hyoscine butylbromide (Buscopan, poorly absorbed by mouth) and hyoscine hydrobromide (patch, tablets). US patch label: no rise in birth defects in observational data; avoid in severe pre-eclampsia (seizures after injection). UK Buscopan: not recommended in pregnancy as a precaution.
- Allattamento
- Safe Hyoscine passes into milk. LactMed: a single dose is unlikely to affect breastfeeding, but long-term use may reduce milk supply or let-down; watch for poor feeding and weight gain. UK Buscopan: not recommended while breastfeeding (no data).
Effetti indesiderati segnalati
- Drowsiness
- Dry mouth
- Blurred vision
- Dizziness
- Disorientation
Controindicazioni
- Hypersensitivity to scopolamine, belladonna alkaloids, or any component in formulation
- Closed-angle glaucoma
Chi deve prestare attenzione
- Use caution in patients with benign prostatic hyperplasia, history of seizures or psychosis, ulcerative colitis, hypertension, hyperthyroidism.
- Scopolamine tablets have been discontinued, but Hyoscine N-Butylbromide is still in market.
- May cause CNS depression; caution when operating heavy machinery or tasks which require mental alertness
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (143)
- Benzhydrocodone / acetaminophen + Scopolamine Major
- Buprenorphine long-acting + Scopolamine Major
- Buprenorphine subdermal implant + Scopolamine Major
- Buprenorphine transdermal + Scopolamine Major
- Clozapine + Scopolamine Major
- Fentanyl + Scopolamine Major
- Fentanyl intranasal + Scopolamine Major
- Fentanyl iontophoretic transdermal system + Scopolamine Major
- Fentanyl transdermal + Scopolamine Major
- Fentanyl transmucosal + Scopolamine Major
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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Altri farmaci della stessa classe
Domande frequenti
What is Scopolamine used for?
Scopolamine is a medicine in the class respiratory. It is used for Irritable bowel syndrome, Motion sickness, Nausea & vomiting.
What side effects have been reported with Scopolamine?
Drowsiness, Dry mouth, Blurred vision, Dizziness, Disorientation.
Can Scopolamine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Covers hyoscine butylbromide (Buscopan, poorly absorbed by mouth) and hyoscine hydrobromide (patch, tablets). US patch label: no rise in birth defects in observational data; avoid in severe pre-eclampsia (seizures after injection). UK Buscopan: not recommended in pregnancy as a precaution. Breastfeeding: Safe. Hyoscine passes into milk. LactMed: a single dose is unlikely to affect breastfeeding, but long-term use may reduce milk supply or let-down; watch for poor feeding and weight gain. UK Buscopan: not recommended while breastfeeding (no data).
What does Scopolamine interact with?
MediHelp lists 143 known interactions for Scopolamine. Major: 17 · Moderate: 105 · Minor: 21. The most serious include Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant.
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